Morgan D, Allaby M, Crook S, Casemore D, Healing T D, Soltanpoor N, Hill S, Hooper W
Commun Dis Rep CDR Rev. 1995 Jun 23;5(7):R93-7.
From 1 April to 31 May 1993, 64 cases of cryptosporidiosis were diagnosed within one district health authority. Forty were classified as primary cases, 35 of whom were clustered in an area supplied by a discrete public water supply that supplied the majority of homes in a large town. Most of the water in this supply is abstracted from boreholes and some is filtered before distribution. Households that received mains water from this supply were 15 times more likely to be affected than households nearby that received water from other sources. A case control study demonstrated a dose response relationship between consumption of water obtained from the town supply and risk of illness. Very low concentrations of cryptosporidial oocysts were detected in the water supply on four occasions several weeks after the outbreak. Environmental investigation failed to reveal a likely mechanism for contamination of the water supply.
1993年4月1日至5月31日期间,在一个地区卫生当局辖区内诊断出64例隐孢子虫病病例。其中40例被列为原发性病例,其中35例集中在一个由独立公共供水系统供水的区域,该系统为一个大城镇的大多数家庭供水。该供水系统的大部分水是从钻孔中抽取的,部分水在分配前经过过滤。从该供水系统获得自来水的家庭受影响的可能性是附近从其他水源取水家庭的15倍。一项病例对照研究表明,饮用城镇供水与患病风险之间存在剂量反应关系。疫情爆发数周后,在供水系统中四次检测到极低浓度的隐孢子虫卵囊。环境调查未能揭示供水系统污染的可能机制。