Higgins A J, Lees P, Wright J A
Res Vet Sci. 1984 May;36(3):284-9.
In a series of experiments to examine equine inflammatory exudates for the presence of metabolites of arachidonic acid, including prostaglandin E2 (PGE2), a model for the induction and collection of exudates in ponies has been developed. Multiperforated polypropylene practice golf balls implanted subcutaneously in the mid-neck region were well tolerated and proved to be the most successful model. One such cage was implanted in the neck of each of seven ponies. Inflammatory exudates were induced by injecting 3.0 or 0.5 ml carrageenin into the cages and aspirates collected between three and 48 hours later. These were examined for PGE2-like activity, total protein concentration and leucocytes. All three variables increased following the injection of both dose levels of carrageenin.
在一系列用于检测马炎性渗出物中花生四烯酸代谢物（包括前列腺素E2，即PGE2）的实验中，已开发出一种诱导和收集小马渗出物的模型。将多孔聚丙烯练习高尔夫球皮下植入颈部中部，耐受性良好，且被证明是最成功的模型。在七匹小马的颈部各植入一个这样的球囊。通过向球囊内注射3.0或0.5 ml角叉菜胶诱导炎性渗出物，并在3至48小时后收集吸出物。检测这些吸出物的PGE2样活性、总蛋白浓度和白细胞数量。注射两种剂量水平的角叉菜胶后，所有这三个变量均增加。
