Julander I
Scand J Infect Dis Suppl. 1983;41:49-55.
During 1965-1980, 80 intravenous drug addicts with staphylococcal septicaemia with or without endocarditis were admitted to the Roslagstulls Hospital. The mean age was 28.8 (range 16-57) years. 42 were females and 38 were males. Endocarditis was diagnosed in 36 of 80 (45%) and suspected in 18 of 80 (22.5%). Septicaemia alone was found in the remaining 26 patients (32.5%). The median interval between onset of disease and institution of adequate therapy for patients without endocarditis was four days and for endocarditis cases eight days. Most patients had septic toxic symptoms. Respiratory tract symptoms were most common in patients with tricuspid valve endocarditis. Tricuspid valve engagement, manifested as pulmonary septic embolism, was present in 33 of 36 (91.7%) of the episodes of endocarditis. Among these patients, murmurs were only present in 23. Haematuria was significantly more often found in patients with endocarditis than in other groups of patients. Otherwise, laboratory data could not differentiate between patients with or without endocarditis. The outcome was lethal in five patients (6.3%): Tricuspid endocarditis (one); left-sided endocarditis (two); suspected endocarditis and retrosternal abscess (one); septicaemia (one). An unfavourable outcome was correlated to patient's delay, severe underlying diseases and/or lack of co-operation. By 1983 another 12 of the patients had died, two of them from endocarditis and one from pneumonia.
1965年至1980年期间，80名患有葡萄球菌败血症伴或不伴心内膜炎的静脉注射吸毒者被收治入罗斯拉格斯图尔斯医院。平均年龄为28.8岁（范围16 - 57岁）。42名女性，38名男性。80例中有36例（45%）被诊断为心内膜炎，80例中有18例（22.5%）疑似心内膜炎。其余26例患者（32.5%）仅患有败血症。无心内膜炎患者从发病到开始充分治疗的中位间隔时间为4天，心内膜炎患者为8天。大多数患者有败血症中毒症状。呼吸道症状在三尖瓣心内膜炎患者中最为常见。三尖瓣受累表现为肺脓毒性栓塞，在36例心内膜炎发作中有33例（91.7%）出现。在这些患者中，仅23例有杂音。血尿在心内膜炎患者中比在其他患者组中明显更常见。否则，实验室数据无法区分有心内膜炎和无心内膜炎的患者。5例患者（6.3%）死亡：三尖瓣心内膜炎（1例）；左侧心内膜炎（2例）；疑似心内膜炎合并胸骨后脓肿（1例）；败血症（1例）。不良结局与患者延误、严重基础疾病和/或缺乏合作有关。到1983年，另有12例患者死亡，其中2例死于心内膜炎，1例死于肺炎。
