Jacobs M B, Yeager M
Arch Intern Med. 1984 Aug;144(8):1597-9.
Hickman-Broviac catheters are often used when long-term venous access is required. Although generally safe, catheter-related thrombosis and infection are two of the most frequent and clinically important complications associated with their use. A 47-year-old woman with breast cancer had a Hickman catheter placed for chemotherapy; subsequently, the superior vena caval syndrome developed due to a large thrombus surrounding the catheter tip. A very low dose of streptokinase successfully lysed this clot within 12 hours. A 60-year-old woman with acute myelogenous leukemia had a Hickman catheter placed to facilitate induction and maintenance chemotherapy. Two episodes of catheter-related Staphylococcus epidermidis sepsis later developed, the first of which cleared without removal of the cannula.
当需要长期静脉通路时，常使用希克曼-布罗维阿克导管。尽管通常是安全的，但导管相关的血栓形成和感染是与其使用相关的最常见且临床上重要的两种并发症。一名47岁的乳腺癌女性置入了希克曼导管用于化疗；随后，由于导管尖端周围形成大血栓，发生了上腔静脉综合征。极低剂量的链激酶在12小时内成功溶解了该血栓。一名60岁的急性髓性白血病女性置入了希克曼导管以方便诱导和维持化疗。后来发生了两起与导管相关的表皮葡萄球菌败血症，第一起在未拔除套管的情况下得以清除。
