Volkova M A, Osmanov D Sh, Frenkel' M A, Probatova N A, Pavlovskaia A I
Ter Arkh. 1984;56(6):43-6.
The authors describe a female patient with acute lymphoblastic leukemia. After the first chemotherapy cycle according to the VAMP program the patient developed a complete remission. Further on, repeated extramedullary relapses (neuroleukemia, involvement of the mammary gland tissue and lymph nodes of the mesentery) were observed over 7 years, the data of blood and bone marrow analyses being within normal. At the end of the disease the patient developed a relapse with changes in the blood and bone marrow, however the blast cells were sudan and peroxidase-positive i.e. could be classified as myeloblasts.
作者描述了一名患有急性淋巴细胞白血病的女性患者。按照VAMP方案进行第一个化疗周期后，患者实现了完全缓解。此后，在7年多的时间里观察到反复的髓外复发（神经白血病、乳腺组织和肠系膜淋巴结受累），血液和骨髓分析数据均在正常范围内。在疾病末期，患者出现血液和骨髓变化的复发情况，然而原始细胞苏丹黑和过氧化物酶呈阳性，即可归类为成髓细胞。
