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内耳液体动力学与内淋巴积水

Inner ear fluids dynamics and endolymphatic hydrops.

作者信息

Juhn S K

出版信息

Acta Otolaryngol Suppl. 1984;406:26-30. doi: 10.3109/00016488309122997.

DOI:10.3109/00016488309122997
PMID:6591707
Abstract

The inner ear possesses remarkably stable homeostatic mechanisms for the maintenance of the functional integrity of the inner ear end-organs. The inner ear fluid maintains its homeostasis by a variety of subtle regulatory mechanisms, both locally and systemically. Any disturbance in one of these mechanisms can induce the disruption of homeostasis expressed by ionic, osmotic, or metabolic imbalance between the compartments. This can be manifested as membrane displacement or abnormal functions of the inner ear, depending on the degree of the disturbance. Further studies are necessary to clarify these regulatory mechanisms of homeostasis and those conditions which alter homeostasis which can result in the abnormal functions. Further research along this line is essential in order to understand the etiology of endolymphatic hydrops and also to establish guidelines for possible normalization of this pathological status.

摘要

内耳拥有极为稳定的稳态机制,以维持内耳终末器官的功能完整性。内耳液通过多种局部和全身的精细调节机制来维持其稳态。这些机制中的任何一种受到干扰,都可能导致内环境稳态的破坏,表现为各腔室之间离子、渗透压或代谢失衡。这可能表现为内耳的膜移位或功能异常,具体取决于干扰的程度。有必要进一步研究以阐明这些稳态调节机制以及那些改变内环境稳态并可能导致功能异常的情况。沿着这条线进行进一步研究对于理解内淋巴积水的病因以及建立使这种病理状态可能恢复正常的指导原则至关重要。

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1
Inner ear fluids dynamics and endolymphatic hydrops.内耳液体动力学与内淋巴积水
Acta Otolaryngol Suppl. 1984;406:26-30. doi: 10.3109/00016488309122997.
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[The endolymphatic sac: its roles in the inner ear].[内淋巴囊:其在内耳中的作用]
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Immunohistochemical localization of Na+, K+-ATPase in the human endolymphatic sac.人内淋巴囊钠钾ATP酶的免疫组织化学定位
Arch Otorhinolaryngol. 1988;245(4):221-3. doi: 10.1007/BF00463931.