Islam A, Catovsky D, Goldman J M, Galton D A
J Clin Pathol. 1984 Nov;37(11):1259-63. doi: 10.1136/jcp.37.11.1259.
Bone marrow fibre content was studied in 34 patients with acute myeloid leukaemia at presentation and subsequently after chemotherapy and at complete remission. The findings indicate that: some degree of marrow fibrosis is present in about one third of the patients with acute myeloid leukaemia at presentation; effective antileukaemia treatment may result in reversal of marrow fibrosis; and increase in marrow fibre content at diagnosis does not affect haemopoietic regeneration after treatment and achievement of complete remission.
对34例急性髓系白血病患者初诊时、化疗后及完全缓解时的骨髓纤维含量进行了研究。研究结果表明：约三分之一的急性髓系白血病患者初诊时存在一定程度的骨髓纤维化；有效的抗白血病治疗可能导致骨髓纤维化逆转；诊断时骨髓纤维含量增加并不影响治疗后造血再生及完全缓解的实现。
