Krpan-Antonin N, Smokvina M
Bilt Hematol Transfuz. 1983;11(2-3):71-8.
The group of 31 patients with acute leukemia was analysed: 24 ALL and 5 ANLL. The complete remission was achieved in 84% of children. Mortality in induction was high and reached 16%. All recidives occurred with in 24 months from the diagnosis. 15% of patients achieve complete continuous remission (CCR) lasting 2 and more years, the result beeing better in patients treated with more intensive regimen. 53% patients will ALL achieved CCR for 5 and more years. In a small group of patients with ANLL the rate of CR is 60%. Only one girl, with a M 3 form lives more than 20 months.
对31例急性白血病患者进行了分析:其中24例为急性淋巴细胞白血病(ALL),5例为急性非淋巴细胞白血病(ANLL)。84%的儿童实现了完全缓解。诱导期死亡率较高,达到16%。所有复发均发生在诊断后的24个月内。15%的患者实现了持续2年及以上的完全持续缓解(CCR),采用更强化方案治疗的患者结果更好。53%的ALL患者实现了5年及以上的CCR。在一小部分ANLL患者中,完全缓解率为60%。只有一名患有M3型的女孩存活超过20个月。