Wolfe F, Cathey M A, Kleinheksel S M
J Rheumatol. 1984 Dec;11(6):814-8.
We studied demographic socioeconomic and clinical characteristics of 38 patients with fibrositis (fibromyalgia) that occurred in association with rheumatoid arthritis (RAFIB) and 242 patients with rheumatoid arthritis (RA) alone. Fewer RAFIB patients were married (57.1%), and most (97.4%) were women. No statistically significant differences in income, medical expenditures or other demographic variables were identified. All measures of function, pain, disease activity and psychological status were more abnormal in RAFIB patients. The clinical characteristics that best differentiated RAFIB and RA patients were pain, depression, anxiety and erythrocyte sedimentation rate, in logistic and stepwise regression models. Evaluation of disease severity markers, including radiographic erosions and frequency of total joint replacement, suggested that disease severity in RAFIB and RA is similar.
我们研究了38例与类风湿性关节炎相关的纤维炎（纤维肌痛）患者（RAFIB）以及242例单纯类风湿性关节炎（RA）患者的人口统计学、社会经济和临床特征。RAFIB患者中已婚者较少（57.1%），且大多数（97.4%）为女性。在收入、医疗支出或其他人口统计学变量方面未发现统计学上的显著差异。RAFIB患者在所有功能、疼痛、疾病活动和心理状态指标上均更为异常。在逻辑回归和逐步回归模型中，最能区分RAFIB和RA患者的临床特征是疼痛、抑郁、焦虑和红细胞沉降率。对包括影像学侵蚀和全关节置换频率在内的疾病严重程度标志物的评估表明，RAFIB和RA的疾病严重程度相似。
