Kumon H, Furukawa M, Mizuno A, Miyata K, Akazawa N, Ohmori H, Katayama Y, Akaeda T
Hinyokika Kiyo. 1984 Sep;30(9):1297-305.
The concentration of DL-8280, a new pyridone carboxylic acid, in the prostatic tissue and fluid after oral administration to man was studied. The drug was concentrated in the prostate and the concentration was dose-dependent. The ratios of prostatic tissue and fluid levels to serum levels were 1.62-1.79 and 1.65-1.96. respectively.