Koppang H S, Stene T, Solheim T, Larheim T A, Winsnes A, Monn E, Stokke O
Scand J Dent Res. 1984 Dec;92(6):489-95. doi: 10.1111/j.1600-0722.1984.tb01287.x.
The dental features in a hitherto unknown type of renal tubular acidosis (capillary blood pH 7.07-7.15) of proximal type are reported. The patient presented agenesis of three second premolars, delayed development and eruption of permanent teeth, delayed shedding of the primary dentition and severe enamel hypoplasia of the permanent teeth. Apart from exceptionally thin enamel, histologic, fluorescent and polarization microscopic and microradiographic investigation of three primary teeth did not reveal unusual findings. The changes are most probably due to a generalized, acidosis-induced defect in several highly differentiated ectodermal tissues.
报告了一种迄今未知的近端型肾小管性酸中毒（毛细血管血pH值7.07 - 7.15）的牙齿特征。该患者出现三颗第二前磨牙先天缺失、恒牙发育和萌出延迟、乳牙脱落延迟以及恒牙严重釉质发育不全。除了釉质异常薄外，对三颗乳牙进行的组织学、荧光和偏振显微镜及微放射照相检查未发现异常结果。这些变化很可能是由于几种高度分化的外胚层组织中普遍存在的酸中毒诱导缺陷所致。
