一氧化二氮与口服术前用药
Nitrous oxide and oral premedication.
作者信息
Giovannitti J A
出版信息
Anesth Prog. 1984 Mar-Apr;31(2):56-63.
Abstract
Patients frequently require conscious-sedation to achieve anxiety relief in the dental office. There are specific indications, contraindications, advantages, and disadvantages to each sedation modality. Selection of the appropriate anesthetic technique should be individualized for each patient. This paper reviews two important conscious-sedation modalities: oral premedication and nitrous oxide/oxygen inhalation sedation.Pertinent drugs are reviewed and recommendations are made for their use; current researches are presented and new areas for investigation are suggested.
摘要
患者在牙科诊所常常需要进行清醒镇静以缓解焦虑。每种镇静方式都有特定的适应证、禁忌证、优点和缺点。应针对每位患者个体化选择合适的麻醉技术。本文回顾了两种重要的清醒镇静方式：口服术前用药和氧化亚氮/氧气吸入镇静。对相关药物进行了综述并给出了使用建议；介绍了当前的研究并提出了新的研究领域。
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本文引用的文献
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Nitrous oxide inactivates methionine synthetase in human liver.一氧化二氮会使人类肝脏中的甲硫氨酸合成酶失活。
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Physical dependence on nitrous oxide in mice: resemblance to alcohol but not to opiate withdrawal.小鼠对一氧化二氮的身体依赖性：类似于酒精，但不同于阿片类药物戒断反应。
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The effect of naloxone and morphine on convulsions in mice following withdrawal from nitrous oxide.纳洛酮和吗啡对小鼠停用氧化亚氮后惊厥的影响。
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