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[儿童急性淋巴细胞白血病骨病变的预后意义]

[Prognostic significance of osseous lesions in acute lymphoblastic leukemia in children].

作者信息

Mancini A F, Rosito P, Vitelli A, Di Flavio V, Tani G, Lucchi A, Montanelli C

出版信息

Pediatr Med Chir. 1983 Nov-Dec;5(6):547-9.

PMID:6597919
Abstract

Full skeletal survey was performed on 54 children presenting over a 6-year period (1973-1979) with acute lymphoblastic leukaemia (ALL). Findings that were considered attributable to leukaemia included metaphyseal bands, osteolytic lesions and periosteal reactions. One or more of these roentgenographic findings was observed in 24 children (44%). The mean duration of remission and of survival was much shorter in cases with multiple bone involvement (3 or more lesions) than in those where bone involvement was absent or limitated at 1 or 2 bone lesions.

摘要

对54名在1973年至1979年这6年期间患急性淋巴细胞白血病(ALL)的儿童进行了全面骨骼检查。被认为与白血病相关的表现包括干骺端带、溶骨性病变和骨膜反应。24名儿童(44%)观察到一项或多项这些X线表现。多骨受累(3处或更多病变)的病例缓解期和生存期的平均时长比无骨受累或仅有1处或2处骨病变的病例短得多。

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