儿童急性淋巴细胞白血病中骨骼放射学受累的预后意义
Prognostic significance of radiological bone involvement in childhood acute lymphoblastic leukaemia.
作者信息
Masera G, Carnelli V, Ferrari M, Recchia M, Bellini F
出版信息
Arch Dis Child. 1977 Jul;52(7):530-3. doi: 10.1136/adc.52.7.530.
Abstract
In 98 children with acute lymphoblastic leukaemia, aged 1 to 12 years, the prognostic significance of radiological bone involvement was studied. The mean duration of remission and of survival was much shorter in cases with multiple bone involvement (3 or more bones) than in those where bone involvement was absent. In those cases presenting with 1 or 2 bone lesions no statement of prognostic significance can be made at this stage. A radiological skeletal survey should be made in all children presenting with leukaemia to identify those (about 15%) having multiple bone lesions and therefore a poor prognosis, in order that they can be given more intensive therapy.
摘要
对98名年龄在1至12岁的急性淋巴细胞白血病患儿，研究了放射性骨受累的预后意义。多骨受累（3块或更多骨头）的病例，其缓解期和生存期的平均时长比无骨受累的病例短得多。对于那些出现1处或2处骨病变的病例，现阶段无法给出关于预后意义的说明。所有白血病患儿均应进行放射性骨骼检查，以识别出那些有多处骨病变（约15%）因而预后较差的患儿，以便给予他们更强化的治疗。
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