肾脏和肾上腺在原发性高血压体液发病机制中的作用。
Role of kidney and adrenals in the humoral pathogenesis of primary hypertension.
作者信息
Zidek W, Heckmann U, Friemann J, Losse H, Vetter H
出版信息
J Hypertens Suppl. 1984 Dec;2(3):S515-7.
PMID:6599709
Abstract
In 18 spontaneously hypertensive rats (SHR) of the Münster strain the circulation was connected to that of normotensive animals using the carotid arteries and external jugular veins. The circulations were mixed by a peristaltic pump. In this model the normotensive rats were made hypertensive after a 10-min cross-perfusion cross unidentified humoral factors causing vasoconstriction play an essential role for the development of hypertension in SHRs.
摘要
在18只明斯特品系的自发性高血压大鼠（SHR）中，利用颈动脉和颈外静脉将其循环系统与血压正常动物的循环系统相连。通过蠕动泵使循环系统混合。在该模型中，经过10分钟的交叉灌注后，血压正常的大鼠出现了高血压，未明确的引起血管收缩的体液因子对SHR高血压的发生起着至关重要的作用。
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