Grenier P, Cornud F, Lacombe P, Viau F, Nahum H
AJR Am J Roentgenol. 1983 Mar;140(3):467-71. doi: 10.2214/ajr.140.3.467.
Isobutyl-2 cyanoacrylate (IBC) was used to embolize the bronchial arteries of 14 patients with severe hemoptysis. The site of bleeding was supplied by a bronchial artery from the aorta in 11 cases and from a right bronchointercostal trunk in three. IBC was injected after previous reduction of the blood flow in the artery by embolization with particles of dura mater. In all cases, bleeding stopped immediately after occlusion and no spinal cord complications were observed. The results indicate that IBC may be a valuable occluding agent in severe hemoptysis, since it produced virtually permanent occlusion of both the distal and proximal parts of the artery. In 13 patients, bleeding did not recur throughout follow-up periods of 2-17 months. In one patient, it recurred 12 months after embolization but stopped after occlusion of another bronchial artery with IBC. It should be noted, however, that immediately after embolization, five patients experienced violent transient retrosternal burning, and one patient experienced dysphagia and fever for 2 days. Since mediastinal ischemia cannot always be avoided, this procedure must be reserved for cases of severe hemoptysis for which surgical treatment is contraindicated.
异丁基-2-氰基丙烯酸酯（IBC）被用于栓塞14例严重咯血患者的支气管动脉。11例患者出血部位由发自主动脉的支气管动脉供血，3例由右支气管肋间干供血。在用硬脑膜颗粒进行栓塞使动脉血流预先减少后注入IBC。所有病例中，闭塞后出血立即停止，未观察到脊髓并发症。结果表明，IBC可能是严重咯血中一种有价值的闭塞剂，因为它几乎能使动脉的远端和近端部分永久性闭塞。13例患者在2至17个月的随访期内未再出血。1例患者在栓塞后12个月出血复发，但在用IBC闭塞另一支气管动脉后出血停止。然而，应注意的是，栓塞后立即有5例患者出现剧烈的短暂胸骨后烧灼感，1例患者出现吞咽困难和发热2天。由于纵隔缺血并非总能避免，该操作必须仅用于手术治疗禁忌的严重咯血病例。
