Morgan R J, Stephenson L W, Woolf P K, Edie R N, Edmunds L H
J Thorac Cardiovasc Surg. 1983 Apr;85(4):527-31.
Since 1971 we have seen 15 children with the diagnosis of purulent pericarditis. The causative organism was Hemophilus influenzae in seven, Staphylococcus aureus in three, and five were due to other organisms. In one child the diagnosis was unsuspected until autopsy. The other 14 patients were all treated with intravenous antibiotics to which the organism was sensitive. One child had an immediate pericardiectomy because of tamponade. The other 13 patients had pericardiocentesis for diagnosis and initial therapy. Pericardiocentesis alone resulted in recovery of four patients and failed in nine, including all seven patients with H. influenzae. These nine had recurrent tamponade or a persistent picture of sepsis that was unresponsive to repeated pericardiocenteses and necessitated operative intervention. The procedure used was subxiphoid tube drainage in two patients. One recovered and the other required further operation. The remaining seven patients were treated with pericardiectomy. All pericardiectomy patients recovered without complications or recurrent symptoms. Survivors are asymptomatic with no evidence of pericardial constriction. We recommend immediate pericardiocentesis for diagnosis and initial therapy. Early pericardiectomy should be performed if the causative organism is H. influenzae, if tamponade occurs after initial pericardiocentesis, or if fever persists despite appropriate antibiotics.
自1971年以来,我们共诊治了15例诊断为化脓性心包炎的患儿。其中7例的病原体为流感嗜血杆菌,3例为金黄色葡萄球菌,另外5例由其他病原体引起。1例患儿直至尸检时才被确诊。其他14例患者均接受了针对病原体敏感的静脉抗生素治疗。1例患儿因心包填塞立即接受了心包切除术。其他13例患者接受了心包穿刺术以进行诊断和初始治疗。仅心包穿刺术使4例患者康复,9例失败,其中包括所有7例流感嗜血杆菌感染的患者。这9例患者出现反复心包填塞或持续败血症表现,对反复心包穿刺术无反应,需要手术干预。2例患者采用剑突下置管引流术。1例康复,另1例需要进一步手术。其余7例患者接受了心包切除术。所有接受心包切除术的患者均康复,无并发症或复发症状。幸存者无症状,无心包缩窄迹象。我们建议立即进行心包穿刺术以进行诊断和初始治疗。如果病原体为流感嗜血杆菌、初次心包穿刺术后出现心包填塞或尽管使用了适当抗生素仍持续发热,则应尽早进行心包切除术。