Rozhkova V N, Komendantova M V
Farmakol Toksikol. 1983 Mar-Apr;46(2):75-8.
As measured on an inflamed rat paw, voltaren raised the pain sensitivity threshold 4-5-fold, whereas on a non-inflamed paw, 2-2.5-fold. The effect seen was dose-dependent. Methindole yielded to voltaren as regards analgetic action determined on inflamed tissues. The method of mechanical irritation of inflamed tissues modified by the authors provides more complete information on analgetic action of non-steroidal anti-inflammatory agents as compared to other methods.
在发炎的大鼠爪子上进行测量时，扶他林使疼痛敏感性阈值提高了4至5倍，而在未发炎的爪子上提高了2至2.5倍。观察到的效果呈剂量依赖性。在对发炎组织测定的镇痛作用方面，甲吲洛尔不及扶他林。与其他方法相比，作者改进的对发炎组织进行机械刺激的方法能提供关于非甾体抗炎药镇痛作用更完整的信息。
