Nikolov R, Peneva M
Eksp Med Morfol. 1978;17(4):190-4.
The authors examined the analgetic and antiinflammatory action of glaucine. They used the following methods for evaluation the analgetic action: chemical irritation, heating plate, heat-ray irritation, mechanical irritation of the normal and inflammatory tissues, electrical irritation and analgetic test. The following methods were used for evaluation of antiinflammatory action: effect on the edema of the rat paw and granulation phases of the inflammation in rats. Codeine and acetysal were used as control drugs. The results from the experiments showed that glaucine successfully inhibited the granulation phase of inflammation and did not affect edema of the rat paw, induce by yeast beer. The analgetic action of glaucine was weak and without practical significance.
作者研究了青藤碱的镇痛和抗炎作用。他们采用以下方法评估镇痛作用：化学刺激、热板法、热射线刺激、正常组织和炎症组织的机械刺激、电刺激以及镇痛试验。采用以下方法评估抗炎作用：对大鼠爪部水肿和大鼠炎症肉芽形成期的影响。可待因和乙酰水杨酸用作对照药物。实验结果表明，青藤碱成功抑制了炎症的肉芽形成期，且不影响酵母啤酒诱导的大鼠爪部水肿。青藤碱的镇痛作用较弱，无实际意义。
