Murphy M T, Richards D B, Lipton J M
Science. 1983 Jul 8;221(4606):192-3. doi: 10.1126/science.6602381.
Centrally administered alpha-melanocyte stimulating hormone is much more potent in reducing fever than the widely used antipyretic acetaminophen. This finding supports the hypothesis that the endogenous neuropeptide has a role in the limitation of fever and suggests that it may be clinically useful as an antipyretic.
中枢给予的α-黑素细胞刺激素在降低发热方面比广泛使用的退烧药对乙酰氨基酚更有效。这一发现支持了内源性神经肽在限制发热中起作用的假说,并表明它可能作为退烧药具有临床用途。