Vereshchagin N V, Khondkarian O A, Bragina L K, Vavilov S B, Zavalishin I A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1983;83(2):166-70.
The authors carried out computer-tomographic examinations of the head of 115 patients suffering from disseminated sclerosis. Various pathological signs, such as a distention of the cerebral ventricles and the subarachnoidal space, a diminution of the cerebellum volume, and presence of lowered-density foci, were revealed in 72% of the patients. 34 lowered-density foci appeared to be subclinical. The computer-tomographic findings were correlated with the disease phase and duration, and the results of the correlation were analyzed. In the phase of the process exacerbation, the lowered-density foci were found more frequently than in the phase of remission, the frequency increase being statistically significant. The distention of the brain ventricles and subarachnoidal space was observed twice as more frequently in patients with a disease duration of over 5 years, than in patients who were ill for 5 years or less. In 3 patients with the spinal form of the disease, a number of signs of brain affection were revealed on the computer-tomographic examination. The data obtained are discussed.
作者对115例患有播散性硬化症的患者进行了头部计算机断层扫描检查。在72%的患者中发现了各种病理体征，如脑室和蛛网膜下腔扩张、小脑体积减小以及低密度灶的存在。34个低密度灶似乎是亚临床的。将计算机断层扫描结果与疾病阶段和病程进行了关联，并对关联结果进行了分析。在疾病加重期，发现低密度灶的频率高于缓解期，频率增加具有统计学意义。病程超过5年的患者脑室和蛛网膜下腔扩张的观察频率是病程5年或更短患者的两倍。在3例脊髓型疾病患者中，计算机断层扫描检查发现了一些脑部病变的体征。对所获得的数据进行了讨论。
