Cleveland R H, Kushner D C, Schwartz A N
AJR Am J Roentgenol. 1983 Jul;141(1):53-6. doi: 10.2214/ajr.141.1.53.
This retrospective study of 470 children undergoing barium upper gastrointestinal examinations was performed with three goals in mind: (1) to document the incidence of gastroesophageal reflux discovered during standardized upper gastrointestinal examination; (2) to compare the amount of gastroesophageal reflux detected in patients with symptoms suggestive of reflux as opposed to those who had no such symptoms; and (3) to ascertain the effect on reflux of the presence of a lower esophageal "beak." About 65% of the children studied had gastroesophageal reflux. Reflux was seen more commonly when symptoms of reflux were present (75.9%) than when not (36.8%). The amount of reflux seen over 5 min was greater if symptoms were present (mean incidence 2.72 bouts) than when not (mean incidence 0.76 bouts). Most importantly, there was a significant decrease in the amount of reflux seen with increase in patient age; age-related criteria for "acceptable" gastroesophageal reflux are presented. The presence of an esophageal "beak" is associated with an increased amount of reflux (94.4%) as opposed to no such "beak" (67.8%). The data suggest that gastroesophageal reflux is present in a large percentage of pediatric patients, whether there are symptoms to suggest reflux or not. Since reflux diminishes with increasing age, age-related criteria for an "acceptable" amount of reflux should be used rather than a universal judgment based on three episodes. Reflux to the cervical esophagus occurs frequently, both with and without symptoms of reflux, and may not be a reliable solitary indication for therapy. An esophageal "beak" is associated with an increase in reflux and may have important prognostic implications.
这项针对470名接受钡剂上消化道检查的儿童的回顾性研究,是带着三个目标进行的:(1)记录在标准化上消化道检查中发现的胃食管反流发生率;(2)比较有反流症状提示的患者与无此类症状的患者中检测到的胃食管反流量;(3)确定食管下段“鸟嘴征”的存在对反流的影响。约65%接受研究的儿童存在胃食管反流。有反流症状时反流更常见(75.9%),无反流症状时则较少见(36.8%)。有症状时5分钟内观察到的反流次数更多(平均发生率2.72次),无症状时则较少(平均发生率0.76次)。最重要的是,随着患者年龄增加,反流量显著减少;文中给出了与年龄相关的“可接受”胃食管反流标准。食管“鸟嘴征”的存在与反流量增加相关(94.4%),而无此“鸟嘴征”时反流量为(67.8%)。数据表明,无论有无反流症状提示,很大比例的儿科患者都存在胃食管反流。由于反流随年龄增长而减少,应采用与年龄相关的“可接受”反流量标准,而非基于三次发作的普遍判断。无论有无反流症状,食管颈段反流都很常见,可能不是可靠的单一治疗指征。食管“鸟嘴征”与反流增加相关,可能具有重要的预后意义。