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颈动脉内膜切除术后的预期寿命和晚期中风

Life expectancy and late stroke following carotid endarterectomy.

作者信息

Bernstein E F, Humber P B, Collins G M, Dilley R B, Devin J B, Stuart S H

出版信息

Ann Surg. 1983 Jul;198(1):80-6. doi: 10.1097/00000658-198307000-00016.

Abstract

A review of the UCSD experience with 456 consecutive carotid endarterectomy procedures confirms the acceptably low operative mortality and morbidity associated with this operation. Immediate complications were not different when routine or selective shunting was performed, but the patients with a low internal carotid artery back pressure had higher operative complication rates. The coexistence of atherosclerosis in other parts of the body severe-enough to warrant surgery for them was not associated with either higher early or late carotid surgery complication rates. Following both coronary bypass and carotid procedures, the late mortality was decreased, and the late incidence of stroke was particularly low in comparison to the remainder of the patient group. Late follow-up emphasized the high continuing attrition rate from all causes in these patients. Late strokes continued to occur, particularly in patients with prior strokes and severe preoperative bilateral carotid disease. The late course of patients with posterior circulation transient ischemic attacks treated by carotid endarterectomy was quite similar to that of patients treated for anterior circulation transient ischemia attacks (TIAs). Newer postoperative screening procedures may decrease the incidence of late postoperative stroke by identifying recurrent carotid stenosis while it is still in the asymptomatic stage.

摘要

对加州大学圣地亚哥分校连续进行的456例颈动脉内膜切除术的经验回顾证实,该手术的手术死亡率和发病率较低,可接受。常规分流或选择性分流时,即刻并发症并无差异,但颈内动脉背压较低的患者手术并发症发生率较高。身体其他部位存在严重到足以需要手术治疗的动脉粥样硬化,与颈动脉手术的早期或晚期并发症发生率升高均无关。在冠状动脉搭桥手术和颈动脉手术后,晚期死亡率降低,与其余患者组相比,晚期中风发生率尤其低。晚期随访强调了这些患者因各种原因导致的持续高损耗率。晚期中风仍会发生,尤其是既往有中风史和术前双侧颈动脉严重病变的患者。接受颈动脉内膜切除术治疗的后循环短暂性脑缺血发作患者的晚期病程与接受前循环短暂性脑缺血发作(TIA)治疗的患者非常相似。更新的术后筛查程序可能通过在复发性颈动脉狭窄仍处于无症状阶段时识别它来降低术后晚期中风的发生率。

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