锝-99m人血清白蛋白：一种适用于人体血浆容量测量的试剂。
Tc-99m human serum albumin: a suitable agent for plasma volume measurements in man.
作者信息
Yang S S, Nickoloff E L, McIntyre P A, Maddrey W C, Mikesell H H, Scheffel U, Kasecamp W, MacAllister N P
出版信息
J Nucl Med. 1978 Jul;19(7):804-7.
In 16 patients we have carried out simultaneous plasma-volume measurements with human serum albumins tagged with Tc-99m (Tc-99m HSA) and I-131 (I-131 HSA). The correlation coefficient was 0.987. Tc-99m HSA, prepared from kits that predictably yield high labeling efficiency (and thereby negligible amounts of TCO4-), is clearly a superior agent for repeat plasma volume determinations, because of its shorter half-life and the reduced radiation dose to the subject.
我们对16名患者同时进行了血浆容量测量，分别使用了标记有锝-99m（Tc-99m人血清白蛋白）和碘-131（I-131人血清白蛋白）的人血清白蛋白。相关系数为0.987。由试剂盒制备的Tc-99m人血清白蛋白可预测地产生高标记效率（从而使高锝酸盐含量可忽略不计），显然是用于重复血浆容量测定的更优试剂，因为其半衰期较短且对受试者的辐射剂量降低。
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