Jenkins C D, Stanton B A, Klein M D, Savageau J A, Harken D E
Psychosom Med. 1983 May;45(2):141-53. doi: 10.1097/00006842-198305000-00006.
Biomedical, behavioral, and psychological correlates of angina pectoris were identified in 204 men awaiting coronary artery by-pass graft surgery. Angina was rated by use of a precoded series of interview questions. Four circumstances of anginal symptoms were investigated: exertional, emotional, post-prandial, and while resting or sleeping. These were uncorrelated with one another, except for exertional and post-prandial. Two-thirds of these patients experienced angina less often than daily in the most recent unrestricted month. Severity of coronary artery obstruction was not positively associated with frequency or severity of any type of angina, and were primarily behavioral and psychological. Disturbances of sleep, physical inactivity, history of cigarette smoking, distressed response to life crises, life dissatisfactions, hostility, use of propranolol, duration of cardiac illness, and age were among the predictors in the multiple regression equations. These results from selected by-pass candidates may apply more directly to such persons than to unselected community residents reporting angina symptoms. The findings suggest the need for greater focus on sources of variability in myocardial oxygen supply and demand in understanding the dynamics of angina episodes.
在204名等待冠状动脉搭桥手术的男性中,确定了心绞痛的生物医学、行为学和心理学相关因素。通过一系列预先编码的访谈问题对心绞痛进行评分。研究了心绞痛症状的四种情况:运动时、情绪激动时、餐后以及休息或睡眠时。除运动时和餐后的情况外,这些情况彼此不相关。在最近一个无限制的月份里,三分之二的这些患者心绞痛发作频率低于每天一次。冠状动脉阻塞的严重程度与任何类型心绞痛的频率或严重程度均无正相关,且主要是行为学和心理学方面的。睡眠障碍、身体活动不足、吸烟史、对生活危机的痛苦反应、生活不满意、敌意、使用普萘洛尔、心脏病病程以及年龄等是多元回归方程中的预测因素。这些来自选定搭桥手术候选者的结果可能比对报告有心绞痛症状的未选定社区居民更直接地适用于此类人群。研究结果表明,在理解心绞痛发作的动态过程中,需要更加关注心肌供需氧变异性的来源。