George D, Glass D
Clin Rheum Dis. 1983 Apr;9(1):177-98.
Complement proteins serve a critical function in the non-antigen-specific elimination of foreign substances and organisms and of immune complexes. Studies of genetic and acquired alterations of complement proteins have provided insights into the pathophysiology of a number of rheumatic diseases, especially those in which immune complexes are believed to have a role in pathogenesis. Complement levels may be helpful in the management of some patients with SLE or vasculitis, and in evaluation of synovial, pleural and pericardial fluids.
补体蛋白在非抗原特异性清除外来物质、生物体及免疫复合物方面发挥着关键作用。对补体蛋白遗传和后天改变的研究为多种风湿性疾病的病理生理学提供了见解，尤其是那些认为免疫复合物在发病机制中起作用的疾病。补体水平可能有助于某些系统性红斑狼疮或血管炎患者的管理，以及滑膜液、胸腔积液和心包积液的评估。
