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The effect of radiation on T cell modulation of Ig synthesis by human B cells in vitro.

作者信息

Wasserman J, Petrini B, von Stedingk L V, Blomgren H, Juhlin I

出版信息

J Clin Lab Immunol. 1983 May;11(1):33-6.

PMID:6603516
Abstract

PWM-induced in vitro Ig synthesis was measured in cell cultures containing B lymphocytes from healthy controls and T lymphocytes collected from breast cancer patients before and after radiotherapy, respectively. The amounts of IgG and IgM did not differ between these two types of cultures. Lymphoid cell suspensions containing 3-5% monocytes were irradiated with 13 Gy and co-cultured with non-irradiated B lymphocytes. The PWM induced production of IgG and IgM in these cultures was decreased as compared to non-irradiated controls.

摘要

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