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[职业性呼吸病理学的当前进展以及新的或未被认识到的风险。煤矿工人尘肺。流行病学和实验方法]

[Current progress and new or unrecognized risks in occupational respiratory pathology. Pneumoconiosis in coal miners. Epidemiologic and experimental approach].

作者信息

Amoudru C

出版信息

Rev Fr Mal Respir. 1983;11(4):355-70.

PMID:6603641
Abstract

In a brief historical review the author shows that the delayed recognition of coal miners pneumoconiosis as an independent nosological entity was mainly due to an insufficiently experimentally orientated approach before 1940. The principal characteristics of the french endemic are described: a slow decline in incidence yet a continued elevated prevalence, due to the increased life span of the sufferers; the late appearance of the first radiological manifestations, most often after the working life of a Miner; a disparity of the endemic levels between mining regions without the reasons being fully elucidated. Finally the principal lines of current research are recalled which take account of new data on epidemiology and modern dust analysis processes as well as information collected in man using recent biological techniques.

摘要

在简要的历史回顾中,作者表明,直到1940年之前,由于实验导向方法不足,煤矿工人尘肺病作为一种独立的病种长期未被认识。文中描述了法国这种地方病的主要特征:由于患者寿命延长,发病率虽有缓慢下降,但患病率持续居高;首次出现放射学表现的时间较晚,大多在矿工结束工作生涯之后;不同矿区地方病流行程度存在差异,其原因尚未完全阐明。最后回顾了当前研究的主要方向,这些研究考虑到了流行病学的新数据、现代粉尘分析方法以及利用最新生物技术在人体收集的信息。

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