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“低剂量可抑制性”高皮质醇血症的随访

A follow-up of the "low dose suppressible" hypercortisolism.

作者信息

Kreze A, Velemínský J, Spirová E

出版信息

Endocrinol Exp. 1983 Jun;17(2):119-23.

PMID:6603966
Abstract

Five subjects with elevated excretion of urinary free cortisol but normal suppressibility to 2 mg dexamethasone test (i.e. with a "low dose suppressible" hypercortisolism) were followed over a period of one to three years. Two of them progressed into a typical pituitary-dependent Cushing's syndrome, whereas in three subjects a spontaneous regression of hypercortisolism was ascertained. A "low dose suppressible" hypercortisolism could therefore denote an early stage of Cushing's syndrome.

摘要

对5名尿游离皮质醇排泄量升高但对2毫克地塞米松试验抑制反应正常(即“低剂量可抑制性”皮质醇增多症)的受试者进行了为期1至3年的随访。其中2人进展为典型的垂体依赖性库欣综合征,而另外3名受试者的皮质醇增多症出现了自发缓解。因此,“低剂量可抑制性”皮质醇增多症可能意味着库欣综合征的早期阶段。

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