Vázquez Chávez C, Miranda Ruíz R, Acevedo Rivera K, Velasco y Aranzolo G R, Brito Zurita O R, López Félix B
Hospital de Cardiología, Centro Médico Nacional Siglo XXI, México, D.F.
Gac Med Mex. 1993 Jul-Aug;129(4):263-6.
Prospective study performed at the General Hospital, National Medical Center, XXI Century, Endocrinology Ward, Mexico-City, to compare the diagnostic sensitivity in Cushing's disease of the oral high doses (8 mg) dexametazone suppression test in single doses with nocturnal administration (DXM-N) and the classic doses of two days (DXM-C). Fourteen patients with hypercortisolism were studied; on thirteen the hypophyseal origin was surgical confirmed. Sensitivity of high doses of oral dexametazone test was proved by using serial samples of serum cortisol; the Fisher test was used for analysis of the suppression of serum cortisol after the test was done.
