同种免疫胸腺细胞对离体小鼠心房的作用。前列腺素的参与。
Effect of alloimmunized thymic cells on isolated mouse atria. Participation of prostaglandins.
作者信息
Genaro A M, Cremaschi G A, Sales M E, Borda E S
出版信息
Experientia. 1983 Sep 15;39(9):1033-5. doi: 10.1007/BF01989789.
PMID:6603987
Abstract
The effects of thymic cells from alloimmunized mice on the mechanical activity of isolated mouse atria were explored. Immune cells decreased the tension without changing the rate of beating of the atrium. After inhibition of prostaglandin synthesis with indomethacin and acetylsalicylic acid, the negative inotropic action of alloimmunized thymic cells was blocked.
摘要
研究了同种免疫小鼠的胸腺细胞对离体小鼠心房机械活性的影响。免疫细胞降低了张力，但未改变心房的搏动频率。在用吲哚美辛和乙酰水杨酸抑制前列腺素合成后，同种免疫胸腺细胞的负性肌力作用被阻断。
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