日本麻风病患者循环免疫复合物和抗核抗体的评估。
Evaluation of circulating immune complexes and antinuclear antibodies in Japanese patients with leprosy.
作者信息
Furukawa F, Sekita K, Hamashima Y, Ozaki M, Imamura S
出版信息
Arch Dermatol Res. 1983;275(3):144-6. doi: 10.1007/BF00510043.
PMID:6604502
Abstract
In 79 patients with leprosy a significant increase of anti-extractable nuclear antigen (ENA) antibodies and circulating immune complexes (CIC) was found. No correlation between CIC and anti-ENA antibodies was demonstrable. Since such a correlation is known from antinuclear antibodies and CIC in patients with systemic lupus erythematosus, it appears likely that anti-ENA antibodies do not play a causative role in CIC-mediated pathogenesis of leprosy.
摘要
在79例麻风病患者中，发现抗可提取核抗原（ENA）抗体和循环免疫复合物（CIC）显著增加。未发现CIC与抗ENA抗体之间存在相关性。鉴于系统性红斑狼疮患者的抗核抗体与CIC之间存在这种相关性，抗ENA抗体似乎不太可能在麻风病的CIC介导的发病机制中起致病作用。
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