Bishop R J, Golden C J, MacInnes W D, Chu C C, Ruedrich S L, Wilson J
Psychiatry Res. 1983 Jul;9(3):225-31. doi: 10.1016/0165-1781(83)90047-1.
The present study was an attempt to investigate hypotheses about the interrelationship of brain dysfunction and symptoms of schizophrenia using the Brief Psychiatric Rating Scale (BPRS) and a measure of cerebral ventricular size. The ventricular brain ratio (VBR) was correlated with admission and discharge scores on the BPRS in 46 schizophrenic patients. A significant relationship was found between VBR and discharge BPRS scores. In general, the results were partially supportive of relationships found between neuropsychological data and the BPRS in a previous study, but shed little light on the relationships between brain damage and negative and positive symptoms. Limitations of using the BPRS, as well as possible sampling variations, are discussed.
本研究试图利用简明精神病评定量表（BPRS）和脑室大小测量方法来探究关于脑功能障碍与精神分裂症症状之间相互关系的假说。对46例精神分裂症患者的脑室脑比率（VBR）与BPRS的入院及出院评分进行了相关性分析。发现VBR与出院时的BPRS评分之间存在显著关系。总体而言，这些结果部分支持了之前一项研究中神经心理学数据与BPRS之间的关系，但对于脑损伤与阴性及阳性症状之间的关系几乎没有提供新的见解。文中讨论了使用BPRS的局限性以及可能存在的抽样差异。
