Cerebral atrophy and neuropsychological correlates in schizophrenia.

Twenty-three patients with DSM III chronic schizophrenia, were given the Wechsler Adult Intelligence Scale and had CT brain scans performed in order to measure the size of the 3rd and 4th ventricles and ventricular brain ratio (VBR). CT-scans showed an evident enlargement of the 3rd ventricle and a VBR overall significantly above that found in normal sample. No significant correlation between ventricular size and cognitive impairment was found. Possible meanings of these findings will be discussed in this paper.