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一种积极的、非分流的控制食管静脉曲张出血的方法。

An aggressive, nonshunting approach for control of bleeding esophageal varices.

作者信息

Wexler M J, Miller N, McLean A P

出版信息

Surg Gynecol Obstet. 1983 Oct;157(4):341-50.

PMID:6604950
Abstract

Morbidity and mortality from variceal hemorrhage can be significantly reduced. A well-defined treatment protocol which obviates delay, procrastination and excessive blood loss is essential. Early aggressive endoscopic sclerotherapy is extremely safe and effective in controlling the acute hemorrhagic event. However, technical details remain to be standardized; rebleeding can be significant and sclerosing until roentgenologic obliteration is essential. Stapled esophageal transection and coronary vein ligation are a reasonable and effective surgical approach when necessary; however, the exact timing and place of this procedure in the therapeutic schema are not yet defined. It requires further phase one studies and not more randomized control trials! It can be difficult after recent sclerotherapy and would appear to require upper gastric devascularization or perhaps percutaneous embolization if gastric varices are venographically prominent. We have recently attempted to modify the procedure in such patients by stapling across the anterior and posterior gastric walls as an alternative or addition to complete esophageal transection. This is accomplished through a small gastrotomy adjacent to the gastroesophageal junction. Shunting procedures or more extensive surgical intervention does not appear necessary, desirable or warranted at this time; however, longer follow-up study is essential.

摘要

静脉曲张出血导致的发病率和死亡率可显著降低。一个明确的治疗方案对于避免延误、拖延和过度失血至关重要。早期积极的内镜下硬化疗法在控制急性出血事件方面极其安全有效。然而,技术细节仍有待标准化;再出血可能很严重,硬化治疗直至放射学上静脉曲张闭塞是必要的。必要时,吻合器食管横断术和冠状静脉结扎术是一种合理有效的手术方法;然而,该手术在治疗方案中的确切时机和位置尚未明确。这需要进一步的一期研究,而不是更多的随机对照试验!近期进行硬化治疗后实施该手术可能会有困难,如果胃静脉曲张在静脉造影中很明显,似乎需要进行胃上部去血管化或经皮栓塞术。我们最近试图通过在胃前壁和后壁进行吻合来修改此类患者的手术方法,作为完全食管横断术的替代或补充。这是通过在胃食管交界处附近进行小的胃切开术来完成的。此时,分流手术或更广泛的手术干预似乎没有必要、不可取或不合理;然而,长期随访研究至关重要。

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