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[热损伤后纤毛上皮细胞蛋白质结构的修复]

[Repair of the protein structures of ciliated epithelial cells after heat damage].

作者信息

Arronet N I

出版信息

Tsitologiia. 1983 Jul;25(7):827-31.

PMID:6604972
Abstract

A study has been made of the ability of ciliated pharengial cells of Rana temporaria L. to repair heat injury. The heat injury estimated by cessation of cellular motile activity has been shown to repair, ciliar movements being renewed. The reparation of the ciliar function is due to the restoration of nativity of the intracellular protein structures providing for the ciliar motility. These structures can be repaired only when they are a component of the whole living cell system; they are not capable of spontaneous renativation, however, when isolated as "glycerinized cell models". It is suggested that the reparation of heat injury in these cells is an active process, presumably dependent on the intracellular metabolism.

摘要

对林蛙咽纤毛细胞修复热损伤的能力进行了一项研究。通过细胞运动活性的停止来估计的热损伤已被证明能够修复,纤毛运动得以恢复。纤毛功能的修复是由于恢复了为纤毛运动提供支持的细胞内蛋白质结构的活性。这些结构只有在它们是整个活细胞系统的组成部分时才能修复;然而,当作为“甘油化细胞模型”分离时,它们不能自发恢复活性。有人认为这些细胞中热损伤的修复是一个活跃的过程,大概依赖于细胞内的新陈代谢。

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