Giovarelli M, Becchio L, Forni G
Boll Ist Sieroter Milan. 1983 May 31;62(2):184-9.
In this paper we tested in parallel lymphokine release, proliferation, cytotoxicity and delayed hypersensitivity (DTH) reactions to H-7 antigen in high responder C57Bl/6 female mice. In vivo priming and in vitro restimulation are required in order to activate all the in vitro T-lymphocyte functions, and the ability to locally transfer DTH reactions. By contrast, a discrepancy is found between in vitro and in vivo tests of T-lymphocyte reactivity. In primed mice DTH reactions are evident, whereas no in vitro reactivity to H-Y is detectable.
在本文中，我们同时检测了高反应性C57Bl/6雌性小鼠对H-7抗原的淋巴细胞因子释放、增殖、细胞毒性和迟发型超敏反应（DTH）。为了激活所有体外T淋巴细胞功能以及局部转移DTH反应的能力，需要进行体内致敏和体外再刺激。相比之下，在T淋巴细胞反应性的体外和体内试验之间发现了差异。在致敏小鼠中，DTH反应明显，而对H-Y没有可检测到的体外反应性。
