Coleman D L, Dodek P M, Luce J M, Golden J A, Gold W M, Murray J F
Am Rev Respir Dis. 1983 Nov;128(5):795-9. doi: 10.1164/arrd.1983.128.5.795.
The records of 35 adult male patients with suspected Pneumocystis carinii pneumonia and the acquired immune deficiency syndrome were reviewed to determine the diagnostic utility of fiberoptic bronchoscopy. Twenty-two of the 24 patients (92%) shown to have Pneumocystis pneumonia were diagnosed by bronchoscopy; 20 patients were diagnosed after 1 bronchoscopy and 2 patients after 2 bronchoscopies. The sensitivity of bronchoscopy specimens for diagnosing Pneumocystis pneumonia was 79% for transbronchial biopsies (19 of 24), 78% for transbronchial biopsy touch preparations (7 of 9), 55% for bronchial washings (11 of 20), and 39% for bronchial brushings (7 of 18). The overall sensitivity of fiberoptic bronchoscopy was 85% (22 positive of 26 total bronchoscopies). Complications, occurring during 6 of the 37 bronchoscopies, were slight hemoptysis (1 patient), fever (2 patients), septic shock (1 patient), and pneumothorax (2 patients). Fiberoptic bronchoscopy is a safe and effective procedure for making the early diagnosis of Pneumocystis carinii pneumonia in adult male patients with the acquired immune deficiency syndrome.
回顾了35例疑似卡氏肺孢子虫肺炎和获得性免疫缺陷综合征的成年男性患者的记录，以确定纤维支气管镜检查的诊断效用。在24例确诊为卡氏肺孢子虫肺炎的患者中，22例（92%）通过支气管镜检查确诊；20例患者在1次支气管镜检查后确诊，2例患者在2次支气管镜检查后确诊。支气管镜检查标本诊断卡氏肺孢子虫肺炎的敏感性，经支气管活检为79%（24例中的19例），经支气管活检触片为78%（9例中的7例），支气管灌洗为55%（20例中的11例），支气管刷检为39%（18例中的7例）。纤维支气管镜检查的总体敏感性为85%（37次支气管镜检查中有22次阳性）。在37次支气管镜检查中有6次出现并发症，分别为轻度咯血（1例患者）、发热（2例患者）、感染性休克（1例患者）和气胸（2例患者）。纤维支气管镜检查是对患有获得性免疫缺陷综合征的成年男性患者进行卡氏肺孢子虫肺炎早期诊断的一种安全有效的方法。
