Rosen M J, Tow T W, Teirstein A S, Chuang M T, Marchevsky A, Bottone E J
Thorax. 1985 Aug;40(8):571-5. doi: 10.1136/thx.40.8.571.
Forty eight patients with the acquired immunedeficiency syndrome (AIDS) presented to the Mount Sinai Hospital in New York with persistent cough and dyspnoea or an abnormal chest radiograph, or both. Thirty two (67%) were found to have Pneumocystis carinii pneumonia, either alone or in combination with another pathogen. Of these patients, eight (25%) had a normal chest radiograph. Abnormalities in the single breath carbon monoxide diffusing capacity and alveolar-arterial oxygen gradient [A-a) DO2) suggested infection with Pneumocystis carinii. Fibreoptic bronchoscopy with transbronchial biopsy was 100% sensitive in the diagnosis of pneumocytis pneumonia. Fibreoptic bronchoscopy should be undertaken in patients suspected of having a pulmonary complication of AIDS, even if the chest radiograph is normal.
48例获得性免疫缺陷综合征(艾滋病)患者因持续咳嗽、呼吸困难或胸部X线片异常或两者兼而有之就诊于纽约西奈山医院。其中32例(67%)被发现患有卡氏肺孢子虫肺炎,或单独感染,或合并其他病原体感染。在这些患者中,8例(25%)胸部X线片正常。单次呼吸一氧化碳弥散量和肺泡-动脉氧分压差(A-a)DO2)异常提示卡氏肺孢子虫感染。经支气管活检的纤维支气管镜检查对肺孢子虫肺炎的诊断敏感性为100%。对于疑似患有艾滋病肺部并发症的患者,即使胸部X线片正常,也应进行纤维支气管镜检查。