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癌症患者和非恶性疾病患者血清中脂质结合唾液酸和急性期蛋白的浓度。

Serum concentrations of lipid bound sialic acid and acute phase proteins in patients with cancer and nonmalignant disease.

作者信息

Raynes J G

出版信息

Biomed Pharmacother. 1983;37(3):136-8.

PMID:6605767
Abstract

Levels of serum lipid bound sialic acid (LSA) were determined in lung cancer and the inflammatory reaction associated with pneumonia, rheumatoid arthritis and surgical wounding. The mean levels of serum LSA were raised in all these disorders and levels were closely correlated with serum alpha 1-acid glycoprotein (AGP) r = 0.9. Levels of AGP and LSA rose and fell in parallel following cholecystectomy. The major influence on the concentration of serum lipid bound sialic acid is the intensity of the response to inflammation.

摘要

测定了肺癌患者以及与肺炎、类风湿性关节炎和手术创伤相关的炎症反应患者血清脂质结合唾液酸(LSA)的水平。在所有这些病症中,血清LSA的平均水平均升高,且其水平与血清α1-酸性糖蛋白(AGP)密切相关,r = 0.9。胆囊切除术后,AGP和LSA的水平同步上升和下降。对血清脂质结合唾液酸浓度的主要影响因素是炎症反应的强度。

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