苏呼米猴种群狒狒淋巴瘤前期的免疫学研究。
Immunological investigation of the prelymphoma period in baboons of the Sukhumi monkey stock.
作者信息
Lapin B A, Voevodin A F, Indzhiia L V, Yakovleva L A, Ponomarjeva T I
出版信息
Exp Pathol. 1983;24(2-3):91-6. doi: 10.1016/s0232-1513(83)80021-8.
PMID:6605878
Abstract
In the "pre-lymphoma" period, some high-risk baboons develop changes in their immunity which is expressed, in particular, in the imbalnace of T-lymphocyte subpopulations, that is, increase in the number of cells of T gamma subpopulation which are carriers of suppressive functions in man. As a reflection of immunological disturbances, increase in the level of antibodies against HVP, apparently as a result of HVP activation, is observed in baboons in the "pre-lymphoma" period.
摘要
在“淋巴瘤前期”，一些高危狒狒的免疫力会出现变化，具体表现为T淋巴细胞亚群失衡，即Tγ亚群细胞数量增加，而在人类中Tγ亚群细胞是抑制功能的载体。作为免疫紊乱的一种反映，在“淋巴瘤前期”的狒狒中观察到抗人乳头瘤病毒（HVP）抗体水平升高，这显然是HVP激活的结果。
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