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病毒性迷路炎:人类早期病理学

Viral labyrinthitis: early pathology in the human.

作者信息

Karmody C S

出版信息

Laryngoscope. 1983 Dec;93(12):1527-33. doi: 10.1288/00005537-198312000-00001.

DOI:10.1288/00005537-198312000-00001
PMID:6606097
Abstract

The histologic findings in the temporal bones of three patients who died from viral encephalopathy are presented. Pathology was restricted to the scala media, vestibular labyrinth, and internal auditory canal and was considered to be expressions of viral labyrinthitis. The changes were different degrees of degeneration of the organ of Corti, early encapsulation of the tectorial membrane, degeneration of the stria vascularis, and round cell infiltration of the modiolus and contents of the internal auditory canal. A new finding in the organ of Corti and early stages of cystic degeneration of the stria vascularis are documented. In all cases, the saccule was degenerated with sloughing of the otolithic membrane and vestibular labyrinth was involved in varying degrees.

摘要

本文呈现了三名死于病毒性脑病患者颞骨的组织学研究结果。病理学变化局限于中阶、前庭迷路和内耳道,被认为是病毒性迷路炎的表现。这些变化包括不同程度的柯蒂氏器变性、盖膜早期包封、血管纹变性以及蜗轴和内耳道内容物的圆形细胞浸润。文中记录了柯蒂氏器的一项新发现以及血管纹囊性变性的早期阶段。在所有病例中,球囊均发生变性,耳石膜脱落,前庭迷路也有不同程度的受累。

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Viral labyrinthitis: early pathology in the human.病毒性迷路炎:人类早期病理学
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引用本文的文献

1
Magnetic resonance imaging assessment of labyrinthine pathology.内耳病理的磁共振成像评估
Eur Radiol. 1996;6(5):621-30. doi: 10.1007/BF00187661.
2
Detection of pseudorabies virus DNA in the inner ear of intranasally infected BALB/c mice with nucleic acid hybridization in situ.通过核酸原位杂交检测经鼻内感染的BALB/c小鼠内耳中的伪狂犬病病毒DNA。
J Virol. 1986 Jan;57(1):335-9. doi: 10.1128/JVI.57.1.335-339.1986.