Reynes M, Tricottet V, Capron F, Diebold J
Scand J Haematol. 1983 Nov;31(5):501-6. doi: 10.1111/j.1600-0609.1983.tb01552.x.
3 cases of hairy cell leukaemia were studied with ultrastructural immunocytochemical methods using an anti human Ig HRPO-Fab fragment. Ig were detected on the cell surface, in the perinuclear cisterna and endoplasmic reticulum of hairy cells. Evidence of Ig in these sites demonstrates a B-lymphoid differentiation of the leukaemic cells.
运用抗人Ig HRPO - Fab片段,采用超微结构免疫细胞化学方法对3例毛细胞白血病进行了研究。在毛细胞的细胞表面、核周池和内质网中检测到了Ig。这些部位存在Ig的证据表明白血病细胞具有B淋巴细胞分化特征。