青少年慢性关节炎患者中HLA-"DRw6"的增加。
Increase of HLA-"DRw6" in patients with juvenile chronic arthritis.
作者信息
Reekers P, Schretlen E D, van de Putte L B
出版信息
Tissue Antigens. 1983 Oct;22(4):283-8. doi: 10.1111/j.1399-0039.1983.tb01204.x.
Abstract
In 43 patients with pauciarticular and 26 patients with polyarticular juvenile chronic arthritis (JCA), an increased frequency was found for HLA-B27 (36%) in male patients with onset of the disease over 9 years of age. The antigen "DRw6" was observed in high frequency (average 57%) in all subtypes of the disease. Indications for increased frequencies were obtained for DR3 in male JCA (40%) and DR5 (42%) in female JCA patients.
摘要
在43例少关节型和26例多关节型青少年慢性关节炎（JCA）患者中，发现9岁以上发病的男性患者中HLA - B27频率增加（36%）。在该疾病的所有亚型中均观察到“DRw6”抗原的高频率（平均57%）。在男性JCA患者中发现DR3频率增加（40%），在女性JCA患者中发现DR5频率增加（42%）。
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