Blane C E, Jongeward R H, Silver T M
AJR Am J Roentgenol. 1983 Dec;141(6):1313-6. doi: 10.2214/ajr.141.6.1313.
The sonograms of 12 neonates and infants with documented nonneoplastic parenchymal liver diseases, including cytomegalovirus infection, biliary atresia, alpha 1-antitrypsin deficiency, nesidioblastosis, Alagille association, microabscesses, and idiopathic neonatal jaundice, were analyzed by various sonographic criteria. Nine (75%) of the hepatic sonograms were abnormal; however, most showed only one sonographic abnormality. Although it was not possible to distinguish one condition from another sonographically, focal areas of heterogeneity simulating mass lesions and accentuated periportal brightness were the most notable abnormal features. The prime indication for hepatic sonography in this age group continues to be the differentiation of obstructive from nonobstructive jaundice. Nonetheless, when obstruction has been excluded, sonography may demonstrate the presence of hepatic parenchymal disease and provide a noninvasive means for following its course over time.
对12例患有已确诊的非肿瘤性肝实质疾病的新生儿和婴儿的超声图像进行了分析，这些疾病包括巨细胞病毒感染、胆道闭锁、α1-抗胰蛋白酶缺乏症、胰岛细胞增殖症、阿拉吉列综合征、微脓肿和特发性新生儿黄疸，分析采用了各种超声标准。9例（75%）肝脏超声图像异常；然而，大多数仅显示一种超声异常。虽然通过超声检查无法区分不同的疾病，但模拟肿块病变的局灶性异质性区域和门静脉周围亮度增强是最显著的异常特征。该年龄组肝脏超声检查的主要指征仍然是区分梗阻性黄疸和非梗阻性黄疸。尽管如此，当排除梗阻后，超声检查可能显示肝实质疾病的存在，并提供一种非侵入性手段来随访其病程。
