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Alagille 综合征患儿 3 岁,肝细胞肝癌合并再生结节。

Hepatocellular carcinoma and regenerating nodule in a 3-year-old child with Alagille syndrome.

机构信息

Division of Diagnostic, Interventional and Pediatric Radiology, Department of Radiology, Neuroradiology and Nuclear Medicine, Bern University Children's Hospital, Freiburgstrasse 10, 3010, Bern, Switzerland.

出版信息

Pediatr Radiol. 2010 Oct;40(10):1696-8. doi: 10.1007/s00247-010-1784-6. Epub 2010 Aug 17.

DOI:10.1007/s00247-010-1784-6
PMID:20714715
Abstract

In Alagille syndrome, routine follow-up imaging of the liver plays an important role in detecting early parenchymal changes and to evaluate portal hypertension. Modern contrast-enhanced imaging methods not only allow early detection of focal liver lesions, but also enable further characterization of their nature and guide biopsy procedures. We present the US and MR imaging findings of hepatocellular carcinoma and a regenerating nodule in a 3-year-old child with Alagille syndrome.

摘要

在 Alagille 综合征中,肝脏的常规随访影像学检查对于早期发现实质改变和评估门静脉高压具有重要作用。现代对比增强成像方法不仅可以早期发现局灶性肝病变,还可以进一步对其性质进行特征描述,并指导活检程序。我们介绍了一名 3 岁 Alagille 综合征患儿肝细胞癌和再生结节的 US 和 MR 成像表现。

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本文引用的文献

1
Tumor-specific vascularization pattern of liver metastasis, hepatocellular carcinoma, hemangioma and focal nodular hyperplasia in the differential diagnosis of 1,349 liver lesions in contrast-enhanced ultrasound (CEUS).对比增强超声(CEUS)对1349例肝脏病变进行鉴别诊断时,肝转移瘤、肝细胞癌、肝血管瘤和局灶性结节性增生的肿瘤特异性血管生成模式
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Hepatocellular carcinoma in liver transplantation candidates: detection with gadobenate dimeglumine-enhanced MRI.肝移植候选者中的肝细胞癌:钆贝葡胺增强MRI检测
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成人阿拉吉耶综合征合并肝细胞癌:病例报告及文献复习
Radiol Case Rep. 2020 Nov 3;16(1):90-93. doi: 10.1016/j.radcr.2020.09.027. eCollection 2021 Jan.
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Nodular macroregenerative tissue as a pattern of regeneration in cholangiopathic disorders.结节状大再生组织作为胆管疾病中的一种再生模式。
Pediatr Radiol. 2018 Jul;48(7):932-940. doi: 10.1007/s00247-018-4129-5. Epub 2018 Apr 19.
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Clinical Applications of Contrast-Enhanced Ultrasound in the Pediatric Work-Up of Focal Liver Lesions and Blunt Abdominal Trauma: A Systematic Review.超声造影在儿童局灶性肝损伤和钝性腹部创伤检查中的临床应用:一项系统评价
Ultrasound Int Open. 2017 Feb;3(1):E2-E7. doi: 10.1055/s-0042-124502.
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Giant hepatic regenerative nodules in Alagille syndrome.阿拉吉耶综合征中的巨大肝脏再生结节。
Pediatr Radiol. 2017 Feb;47(2):197-204. doi: 10.1007/s00247-016-3728-2. Epub 2016 Oct 28.
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Magnetic resonance imaging of pancreaticobiliary diseases in children: from technique to practice.儿童胰胆疾病的磁共振成像:从技术到实践
Pediatr Radiol. 2016 May;46(6):778-90. doi: 10.1007/s00247-016-3608-9. Epub 2016 May 26.
8
Alagille Syndrome Candidates for Liver Transplantation: Differentiation from End-Stage Biliary Atresia Using Preoperative CT.肝移植候选的阿拉吉列综合征:利用术前CT与终末期胆道闭锁进行鉴别
PLoS One. 2016 Feb 22;11(2):e0149681. doi: 10.1371/journal.pone.0149681. eCollection 2016.
Hepatocellular carcinoma in children with Alagille syndrome.
阿拉吉列综合征患儿的肝细胞癌
J Pediatr Gastroenterol Nutr. 2005 Nov;41(5):676-8. doi: 10.1097/01.mpg.0000179759.60048.c4.
4
Hepatocellular carcinoma occurring in alagille syndrome.阿拉吉尔综合征中发生的肝细胞癌。
Pathol Res Pract. 2005;201(1):55-60. doi: 10.1016/j.prp.2004.11.007.
5
Hepatic nodular hyperplasia in a boy with Alagille syndrome: CT and MR appearances.一名患有阿拉吉耶综合征男孩的肝脏结节性增生:CT和MR表现
Pediatr Radiol. 2001 Aug;31(8):584-8. doi: 10.1007/s002470100510.
6
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Leber Magen Darm. 1996 May;26(3):157-8, 161-3.
7
Sonographic features of hepatocellular disease in neonates and infants.新生儿和婴儿肝细胞疾病的超声特征。
AJR Am J Roentgenol. 1983 Dec;141(6):1313-6. doi: 10.2214/ajr.141.6.1313.