Slepushkin A N, Ritova V V, Fedorova G I, Feklisova L V, Obrosova-Serova N P
Vopr Virusol. 1983 Sep-Oct;28(5):564-7.
Blood sera from 317 children with the history of noninfectious diseases or normal children pretreated with RDE were collected and examined for antihemagglutinins to 7 influenza virus strains in order to check the results of studies of 1980 and to study the immunity status to influenza A (H1N1), A (H2N2), A (H3N2) and B in the preepidemic period of 1981. Negative results of antihemagglutinin detection to influenza A/Iksha/1/57 (H2N2) in sera of all the children have confirmed the conclusion made in the previous paper (1) that influenza A (H1N2) viruses have not circulated in recent years among the population of Moscow City and suburban areas. Fourteen sera positive in HI tests with A/Shklyawer/49 virus similar to A/PR/8/34 (H1N1) in titres from 1:20 to 1:40 did not produce hemolysis zones with A/PR/8/34 virus in RHT, but most of these sera gave similar results of both tests with A/Brazil/11/79 and A/Khabarovsk/1/77 viruses. This attests to cross, nonspecific nature of hemagglutination-inhibition with A/Shklyawer/49 virus which evidently does not circulate now in the population of Moscow City and suburbs. An increase in the level of immunity to influenza B and A (H1N1)/1977 viruses reflected the epidemic situation of the previous year.
收集了317名有非传染性疾病史的儿童或经受体破坏酶预处理的正常儿童的血清，检测其对7种流感病毒株的抗血凝素，以检验1980年的研究结果，并研究1981年流行前期对甲型（H1N1）、甲型（H2N2）、甲型（H3N2）和乙型流感的免疫状况。所有儿童血清中对甲型/伊克沙/1/57（H2N2）流感病毒的抗血凝素检测结果均为阴性，这证实了前文（1）得出的结论，即近年来甲型（H1N2）流感病毒在莫斯科市及郊区人群中未传播。14份血清在血凝抑制试验中对与甲型/普里/8/34（H1N1）相似的甲型/什克利亚夫尔/49病毒呈阳性，滴度为1:20至1:40，但在红细胞吸附抑制试验中，这些血清与甲型/普里/8/34病毒未产生溶血区，不过其中大多数血清对甲型/巴西/11/79和甲型/哈巴罗夫斯克/1/77病毒的两种试验结果相似。这证明了与甲型/什克利亚夫尔/49病毒的血凝抑制反应具有交叉、非特异性性质，该病毒目前显然在莫斯科市及郊区人群中未传播。对乙型流感和甲型（H1N1）/1977病毒免疫水平的提高反映了上一年的流行情况。
