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坦桑尼亚甲型和乙型流感抗体状况。

Influenza A and B antibody status in Tanzania.

作者信息

Masurel N

机构信息

Department of Virology, Erasmus Universiteit, Rotterdam, The Netherlands.

出版信息

Trans R Soc Trop Med Hyg. 1987;81(1):75-9. doi: 10.1016/0035-9203(87)90289-6.

Abstract

Sera from 200 babies and young children and from 205 mother-newborn pairs were tested for haemagglutination inhibiting antibody against three A-H1N1, one A-H2N2, four A-H3N2, and two influenza B viruses. The results indicated that a higher concentration of antibody against all influenza A and B viruses tested was found more frequently in maternal sera than in neonatal sera. High prevalences of antibody and high geometric mean titres against the A-H2N2-1957 and A-H3N2-1968 viruses from the eras 1957-1968 and 1968-now, respectively, were found in the age groups above 15 years. The antibodies against former and recent epidemic influenza viruses of the A-H3N2 subtype, found among different adult age groups in Mwanza, Tanzania, showed a pattern similar to that in the population of The Netherlands.

摘要

检测了200名婴幼儿以及205对母婴的血清,以检测其针对三种甲型H1N1、一种甲型H2N2、四种甲型H3N2和两种乙型流感病毒的血凝抑制抗体。结果表明,在母体血清中比在新生儿血清中更频繁地发现针对所有检测的甲型和乙型流感病毒的更高浓度抗体。在15岁以上年龄组中,分别发现了针对1957 - 1968年和1968年至今这两个时期的甲型H2N2 - 1957和甲型H3N2 - 1968病毒的高抗体流行率和高几何平均滴度。在坦桑尼亚姆万扎不同成年年龄组中发现的针对甲型H3N2亚型既往和近期流行流感病毒的抗体,显示出与荷兰人群相似的模式。

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