Burtin C, Soubrane C
Biomedicine. 1976 Dec 15;24(6):405-10.
Anti-drug serum human IgE can be detected by passive sensitization "in vitro" of monkey lung tissue. This technique gives reproducible results which are not quantitative. It is sensible; there are no false positive results and the number of false negative results has been strongly decreased. This technique is really an anaphylaxis and IgE only are detected. The results concern the study of 215 patients which possible drug allergy. The most frequent drugs come from groups of penicillins, sulfonamides, salicylates and malonylurea derivates. In 54% of cases, anti-drug IgE have been detected.
抗药物血清人IgE可通过猴肺组织的“体外”被动致敏来检测。该技术可得出可重复的结果，但并非定量结果。它是合理的；没有假阳性结果，假阴性结果的数量也已大幅减少。该技术实际上是一种过敏反应检测，仅检测IgE。结果涉及对215例可能存在药物过敏的患者的研究。最常见的药物来自青霉素类、磺胺类、水杨酸盐类和丙二酰脲衍生物类。在54%的病例中检测到了抗药物IgE。
