Beyer T L, Vogler G, Sharma D, O'Donnell F E
Invest Ophthalmol Vis Sci. 1984 Jan;25(1):108-12.
Ten eyes of five Rhesus monkeys underwent extracapsular lens extraction. The right eye of each monkey was allowed to retain an intact posterior capsule. The left eye of each monkey had a wide primary capsulectomy with minimal anterior vitrectomy. In order to exclude operative contamination, we waited 2 to 3 weeks later to challenge the eyes with bacteria. Seventy-two hours after anterior chamber injection of equal numbers of Staphylococcus aureus, diagnostic cultures were obtained from the anterior chamber and vitreous and correlated with the clinical findings. Injection of 10,000 S. aureus produced culture-positive endophthalmitis in eyes that had undergone posterior capsulectomy, but it failed to produce endophthalmitis in fellow eyes with intact posterior capsules. This suggest that a significant barrier effect against the development of bacterial endophthalmitis exists in the eyes with intact posterior capsules.
对5只恒河猴的10只眼睛进行了囊外晶状体摘除术。每只猴子的右眼保留完整的后囊。每只猴子的左眼进行了广泛的原发性囊膜切除术并伴有少量前部玻璃体切除术。为排除手术污染，我们在2至3周后用细菌对眼睛进行攻击。在前房注射等量金黄色葡萄球菌72小时后，从前房和玻璃体获取诊断性培养物，并与临床发现进行关联。向进行了后囊膜切除术的眼睛注射10000个金黄色葡萄球菌可产生培养阳性的眼内炎，但在具有完整后囊的对侧眼中未能产生眼内炎。这表明具有完整后囊的眼睛对细菌性眼内炎的发展存在显著的屏障作用。
